Meloxicam

Meloxicam

The prostaglandin synthetase (cylooxygenase 1 and 2) enzymes are inhibited by meloxicam, which results in a reduction in the production of prostaglandins, which typically mediate unpleasant inflammatory symptoms. Inhibiting prostaglandin production has analgesic and inflammatory effects because prostaglandins stimulate neuronal pain receptors. Meloxicam mostly inhibits COX-2, however, it also has some efficacy against COX-1, irritating the stomach.

A non-steroidal anti-inflammatory medicine (NSAID) called meloxicam is used to treat the symptoms of osteoarthritis and rheumatoid arthritis. Additionally, it is applied to patients 2 years of age and older with the pauciarticular and polyarticular forms of juvenile rheumatoid arthritis (JRA). The treatment of dental or post-surgical pain is one example of off-label usage. Meloxicam has also been investigated for the treatment of neuropathic pain in addition to the aforementioned uses.

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