Pharmaceutical R&D and Custom Synthesis Services in India
From lab-scale molecules to scalable, documented processes, Salvavidas Pharma supports pharmaceutical companies with research and development, custom synthesis and technology transfer. Whether you need a hard-to-find intermediate, an impurity standard or a robust route for a new API, our team works with you under strict confidentiality and quality controls.
Why Choose Our R&D and Custom Synthesis Services?
- From idea to scale: support from feasibility and route development through scale-up and technology transfer .
- Confidential by default: projects start with a non-disclosure agreement, and ownership of results is agreed in writing.
- Quality and documentation: clear analytical data, batch records and reports that support your regulatory filings.
- Experience in complex therapy areas: including oncology, anti-HIV/ARV and generic molecules .
- Backed by a WHO-GMP certified manufacturer based in Surat, Gujarat, India, so development can connect to commercial supply.
What We Offer
| Service | What it includes | Typical deliverables |
|---|---|---|
| Custom synthesis | Synthesis of APIs, intermediates and other small molecules to your structure and specification | Material at the agreed purity, analytical data, summary report |
| Process R&D | Route scouting, process optimisation and scale-up studies | Optimised process, process description, yield and impurity data |
| Process R&D | Preparation and characterisation of known and unknown impurities | Characterised sample, supporting analytical data |
| Analytical development | Method development and validation, impurity profiling | Methods, validation summary, specifications |
| Formulation development | Development of tablets, capsules or injectables | Prototype batches, development report |
| Stability studies | Studies to support shelf-life and packaging decisions | Stability protocol and data |
| Technology transfer | Transfer of the process to pilot or commercial scale | Transfer package, batch records, scale-up support |
| Regulatory documentation support | Technical information for dossier and DMF-type filings | Documents aligned with your filing needs |
Custom Synthesis for Pharmaceutical Companies
Custom synthesis means making a specific compound to your requirements, often when it is not available in the catalogue market or when you need a defined purity, form or quantity. Typical requests include:
- new or hard-to-source intermediates and building blocks
- API development for generic launches
- reference standards and process-related impurities
- small batches for research and early development
- larger quantities for validation or commercial supply
Tell us the structure or name, CAS number if available, target purity, quantity and timeline, and we will assess feasibility and respond with a proposal.
Pharmaceutical R&D: From Route to Process
A route that works in the lab is not always a route that works at scale. Our R&D approach focuses on:
- Feasibility and route selection: choosing practical, reproducible chemistry
- Process optimisation: improving yield, purity and robustness
- Impurity understanding: identifying and controlling impurities early, in line with ICH guidance on impurities, residual solvents and elemental impurities
- Scale-up readiness: thinking about safety, equipment and cost before the project moves to larger batches
- Documentation: recording what was done so results can be repeated and transferred
How a Project Works
- Enquiry and NDA: you share the requirement, and both sides sign a confidentiality agreement.
- Scope and feasibility: we review the structure, specification, quantity and timeline, and tell you what is realistic.
- Proposal: scope, deliverables, timeline and commercial terms in writing.
- Development work: route development, synthesis and analytical work at the agreed scale.
- Reporting: progress updates and a final report with analytical data.
- Delivery or transfer: material is delivered, or the process is transferred to larger-scale production.
- Ongoing supply (optional): where suitable, development continues into commercial manufacturing.
Scale Options
| Stage | Purpose | Typical use |
|---|---|---|
| Lab scale | Feasibility and route development | Grams, early evaluation |
| Kilo-lab scale | Process optimisation and sample supply | Kilogram quantities for testing and validation |
| Pilot scale | Process validation and scale-up | Pre-commercial batches |
| Commercial scale | Routine manufacturing | Ongoing supply under GMP |
Quality, Compliance and Confidentiality
- GMP alignment: commercial API manufacturing follows GMP principles such as ICH Q7. Early-stage research work is documented to a standard suitable for later transfer.
- Impurity control: we consider related substances, residual solvents, elemental impurities and mutagenic impurities as part of development.
- Data integrity: raw data, methods and results are recorded and traceable.
- Confidentiality and IP: each project is covered by an NDA, and ownership of intellectual property and results is agreed in the contract before work starts.
- Safety and environment: processes are reviewed for safety, waste handling and environmental requirements.
Who We Work With
- generic and branded pharmaceutical companies
- start-ups and research organisations
- formulators who want a dependable API or intermediate source
- distributors and exporters who need supply from a qualified manufacturer
What to Send With Your Enquiry
To get a fast, useful response, include:
- compound name, structure and CAS number (if available)
- required purity and specification
- quantity and number of batches
- target timeline
- any known synthesis route or literature references
- required analytical data or documents
- your target market and intended use (for example, development, validation or commercial supply)
Frequently Asked Questions
What is custom synthesis in pharma?
Custom synthesis is the manufacture of a specific compound to a customer’s requirements, such as a defined structure, purity and quantity. It is used when a molecule is not readily available or needs special specifications.
What is the difference between R&D and commercial manufacturing?
R&D focuses on developing and understanding a route or formulation, usually in small batches. Commercial manufacturing produces larger, repeatable batches under GMP for sale. A good project plans the move between the two from the start.
Do you sign an NDA before starting?
Yes, projects start with a confidentiality agreement.
Who owns the intellectual property?
Ownership of results and intellectual property is agreed in writing before work starts, according to the contract for each project.
Can you scale a developed process to commercial production?
Where suitable, a process developed in R&D can be transferred to larger-scale production, and we can discuss ongoing supply.
How long does a custom synthesis project take?
It depends on the molecule, complexity and scale. We confirm a timeline in the proposal after reviewing your requirements.
Can you supply impurity standards?
Send us the impurity name or structure and we will confirm feasibility.
Which markets do you support?
We supply customers in India and export markets including Africa. For registration, we can discuss the documents your regulator requires.Â
How to Take Vitamin D3 Safely
How Much Do Adults Need?
For most healthy adults, 600 IU (15 mcg) a day covers basic needs, and adults over 70 need about 800 IU. The usual safe upper limit for adults is 4,000 IU a day from all sources combined.
Common Strengths in India
Daily products usually come in 400 IU, 1,000 IU or 2,000 IU. The 60,000 IU weekly dose is for treatment, and your doctor should recheck your blood after two months to see if vitamin D3 deficiency symptoms have eased.
Best Time to Take It
Timing matters less than consistency. Take your dose with your largest meal, because fat helps absorption. If you miss a daily dose, don’t double up the next day. Just carry on as normal.
Signs Your Dose Is Working
Energy and muscle aches often improve within a few weeks, though bone changes take months. The only reliable proof is a repeat blood test, so don’t judge progress by how you feel alone.
Side Effects and Warning Signs
At normal doses, D3 rarely causes trouble. Problems start after months of very high intake, which can push blood calcium too high and cause nausea, constant thirst, confusion or kidney stones.
These signs need prompt medical attention. They’re also the main reason long-term high-dose vitamin D3 capsules should never be self-prescribed, no matter what a friend or a social media post suggests.
Start Your Project
Share your molecule, quantity and timeline with our team and we will respond with next steps.